Temoside 20mg Capsule 5’S

WHAT IS TEMOSIDE 20MG?

TEMOSIDE 20MG contains temozolomide which belongs to an anti-tumor agent

WHAT TEMOSIDE 20MG IS USED FOR?

TEMOSIDE 20MG is used for the treatment of specific forms of brain tumors such as,

Newly-diagnosed glioblastoma multiforme
Anaplastic astrocytoma
TEMOSIDE 20MG is used in these tumors if they return or get worse after standard treatment.

WARNINGS AND PRECAUTIONS:

TALK TO DOCTOR

Talk to your doctor before taking this medicine, if you:

Are allergic to temozolomide or any of the other ingredients of this medicine
Have had an allergic reaction to dacarbazine (an anticancer medicine sometimes called DTIC)
Have severely reduced blood cells (myelosuppression), such as your white blood, red blood and platelet count
Have serious form of chest infection called Pneumocystis jirovecii pneumonia (PCP)
Have ever had or might now have a hepatitis B infection
May have a small risk of other changes in blood cells, including leukemia
More prone to infections, bruising or bleeding
Have liver or kidney problems

PREGNANCY & BREAST FEEDING

Effective contraceptive precautions must be taken by patients who are taking TEMOSIDE 20MG
You should stop breast-feeding while receiving treatment with TEMOSIDE 20MG
If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine

CHILDREN & ADOLESCENTS

Do not give this medicine to children under the age of 3 years because it has not been established

DRIVING & USING MACHINES

TEMOSIDE 20MG may make you feel tired or sleepy. In this case, do not drive or use any tools or machines or cycle until you see how this medicine affects you

INTERACTIONS:

Tell your doctor if you are taking, have recently taken or might take any other medicines including medicine obtained without prescription, vitamin supplements and herbal products

DIRECTIONS & FOR USE:

Always take this medicine exactly as your doctor has told you
Your doctor will work out your dose of TEMOSIDE 20MG. This is based on your size (height and weight) and if you have a recurrent tumor and have had chemotherapy treatment in the past
Take your prescribed dose of TEMOSIDE 20MG once a day, preferably at the same time each day
Take this medicine on an empty stomach; for example, at least one hour before you plan to eat breakfast. Swallow it whole with a glass of water
Do not open, crush or chew the medicine

If you take more TEMOSIDE 20MG

If you accidentally take more TEMOSIDE 20MG than you were told to, contact your doctor immediately

If you forget to take TEMOSIDE 20MG

Take the missed dose as soon as possible during the same day
Do not take a double dose to make up for a forgotten dose, unless your doctor tells you to do so

If you stop taking TEMOSIDE 20MG

Do not stop taking this medicine unless your doctor has told you to do so

SIDE EFFECTS OF TEMOSIDE 20MG:

SERIOUS

• A severe allergic (hypersensitive) reaction (hives, wheezing or other breathing difficulty)
• Uncontrolled bleeding
• Seizures (convulsions)
• Fever, chills
•  Severe headache that does not go away
• A reduction in certain kinds of blood cells. This may cause you to have increased bruising or bleeding, anemia (a shortage of red blood cells), fever, and reduced resistance to infections

COMMON

• Infections, wound infection
• Increased sugar in the blood, loss of weight
• Change in mental status or alertness, anxiety/depression, sleepiness, difficulty speaking, impaired balance, dizziness, confusion, forgetfulness, difficulty concentrating
• Inability to fall asleep or stay asleep, tingling sensation, bruising, shaking, abnormal or blurry vision, double vision
• Hearing impairment
• Shortness of breath, cough
• Blood clot in the legs, fluid retention, swollen legs
•  Stomach upset
• Difficulty swallowing, dry mouth
• Skin irritation or redness, dry skin, itching
• Muscle weakness, painful joints, muscle aches and pains
• Frequent urination, difficulty with holding your urine
• Allergic reaction, fever,
• Radiation injury, face swelling, pain
• Abnormal taste
• Reduced number of blood cells (neutropenia or lymphopenia, thrombocytopenia)

UNCOMMON

• Flu-like symptoms, red spots under the skin
•  Low potassium level in the blood, weight gain
• Mood swings, hallucination and memory impairment, partial paralysis, impaired coordination, impaired sensations, partial loss of vision
• Dry or painful eyes, deafness, infection of the middle ear, ringing in the ears, earache, palpitations (when you can feel your heart beat)
• Blood clot in the lung, high blood pressure, pneumonia, inflammation of your sinuses, bronchitis, a cold or the flu
• Swollen stomach, difficulty controlling your bowel movements, hemorrhoid’s
•  Peeling skin, increased skin sensitivity to sunlight, change in skin color, increased sweating
• Muscle damage, back pain
• Vaginal bleeding, sexual impotence, absent or heavy menstrual periods, vaginal irritation, breast pain
• Hot flushes, shivering, discoloration of your tongue, change in your sense of smell, thirst, tooth disorder

RARE

• Cough, infections including pneumonia

VERY RARE

• Skin redness, urticaria (hives), skin eruption, allergic reactions

STORAGE:

Keep this medicine out of reach of children
Do not use this medicine after the expiry date
Store at room temperature (15-25°C)