Diapride M 0.5 Tablet 15’s is a combination of two anti-diabetic drugs: Glimepiride and Metformin. Glimepiride, which is a ‘sulfonylurea’, acts by increasing the amount of insulin released by the pancreas. Metformin, which is a ‘biguanide’, acts by lowering the glucose production in the liver, delaying glucose absorption from the intestines and increasing the body’s response to insulin. In a nutshell, the two medicines together prevent the blood glucose levels from rising to very high levels thus keeping your Diabetes under control.
Type 2 diabetes is a chronic or lifelong condition that affects the way your body processes glucose. People with type 2 diabetes either do not produce enough insulin or if at all the insulin is produced, it is unable to perform its function in the body (insulin resistance). Due to this, the blood glucose level increases and symptoms such as frequent urination, increased thirst and increased hunger start. It can lead to serious complications like skin infection, eye problems (retinopathy), nerve damage (neuropathy), diabetic foot (foot ulcer), kidney disease (nephropathy), high blood pressure, and even stroke.
By the above-mentioned mechanisms, the two medicines in Diapride M 0.5 Tablet 15’s act together to keep your blood sugar levels under check. The strict control of blood sugars is especially important to mention the many disabling side effects of Diabetes. Diapride M 0.5 Tablet 15’s shows optimum effects when taken along with healthy lifestyle changes like weight loss, regular exercise, healthy diet etc.
Diapride M 0.5 Tablet 15’s should be taken with food to avoid an upset stomach. Diapride M 0.5 Tablet 15’s should be taken at the same time of the day each time for the best results. For better advise, your doctor will decide what dose should be taken and it can change timely depending upon your condition. A common side effect of Diapride M 0.5 Tablet 15’s is hypoglycaemia (low blood glucose levels) characterized by dizziness, sweating, palpitations, hunger pangs, dry mouth and skin etc. So, to avoid hypoglycaemia, you should not miss meals and also should carry some form of sugar along with you. Other side effects include taste change, nausea, diarrhoea, stomach pain, headache, upper respiratory symptoms.
Diapride M 0.5 Tablet 15’s should not be stopped even if you feel better, without consulting your doctor as sugar level keeps changing. If you stop taking Diapride M 0.5 Tablet 15’s abruptly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy) and nerve damage (neuropathy). Diapride M 0.5 Tablet 15’s should not be taken if you have type 1 diabetes mellitus, severe kidney or liver disease. Please inform your doctor if you have any type of heart disease, is or are planning to get pregnant or are breastfeeding.
Uses of Diapride M 0.5 Tablet 15’s
Diabetes Mellitus Type 2
Medicinal Benefits
Diapride M 0.5 Tablet 15’s helps in controlling blood sugar level without any weight gain. Besides this, it is also cardio-protective preventing the heart from further complications. Diapride M 0.5 Tablet 15’s also helps to prevent serious complications of diabetes such as kidney damage (Diabetic Nephropathy), blindness (Diabetic Retinopathy), loss of sensation in your hands and feet (Diabetic Neuropathy) or even loss of foot! Diapride M 0.5 Tablet 15’s also helps to reduce your chance of having a heart attack or stroke. Being a combination of two drugs, it reduces the need to take multiple pills and hence makes it easier to remember to take the drugs.
Directions for Use
Take Diapride M 0.5 Tablet 15’s as advised by your doctor. Preferably take it with a meal to minimize stomach upset. Swallow it as a whole with a glass of water. Do not chew or crush it. In case you missed taking Diapride M 0.5 Tablet 15’s do not double the dose as it may decrease your blood sugar level (hypoglycaemia) which can be fatal.
Storage
Store in a cool and dry place away from sunlight
Side Effects of Diapride M 0.5 Tablet 15’s
Most of the side effects of Diapride M 0.5 Tablet 15’s do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. A common side effect of Diapride M 0.5 Tablet 15’s is hypoglycaemia (low blood glucose level) characterized by dizziness, sweating, palpitations, hunger pangs, dry mouth and skin etc. Some people may also experience taste change, nausea, diarrhoea, stomach pain, flatulence, headache, upper respiratory symptoms, skin rash etc. It is not necessary for everyone to experience the above side effects. In case of any discomfort, speak with your doctor.
In-Depth Precautions and Warning
Drug Warnings
Some diabetic patient taking Diapride M 0.5 Tablet 15’s may develop a serious condition called lactic acidosis. In lactic acidosis, there is too much of lactic acid accumulated in the blood. So, your liver and kidney proper functioning is required for the elimination of excess lactic acid from the blood. You should not take metformin if you have kidney disease, as measured by a blood test. Diapride M 0.5 Tablet 15’s may lower vitamin B12 levels, so try to have blood test annual blood and vitamin. Metformin when used with insulin may extremely lower the blood sugar level. So, the doctor may lower the dose of insulin.
Drug Interactions
Drug-Drug Interaction: Diapride M 0.5 Tablet 15’s may interact with insulin, high blood pressure lowering pills (hydrochlorothiazide, amlodipine), water pills/diuretics (furosemide), heart failure-related medicines (digoxin), anti-hypertensive (metoprolol), steroids (prednisolone), thyroid hormones etc. So, tell your doctor if you are using these drugs before taking Diapride M 0.5 Tablet 15’s.
Drug-Food Interaction: Taking Diapride M 0.5 Tablet 15’s with alcoholic beverages may increase the risk of a rare but serious and potentially life-threatening condition known as lactic acidosis (build-up of lactic acid in the blood) and hypoglycaemia.
Drug-Disease Interaction: Diapride M 0.5 Tablet 15’s should be avoided in patients with vitamin B12 deficiency, kidney problems, liver problem, cardiovascular disease (heart related issues), and low blood sugar level (hypoglycaemia) as it may worsen the condition.
Safety Advice
ALCOHOL
CONSULT YOUR DOCTOR
Diapride M 0.5 Tablet 15’s should not be taken until prescribed if you are taking alcohol. Taking Diapride M 0.5 Tablet 15’s with alcohol can cause hypoglycaemia and can also lead to a rare but life-threatening condition known as Lactic Acidosis. So, keep your doctor informed if you drink alcohol.
PREGNANCY
Diapride M 0.5 Tablet 15’s is not recommended during pregnancy. However, your doctor may prescribe it for you during pregnancy if he/she feels that the benefit to you outweighs the risk. You should not take Diapride M 0.5 Tablet 15’s without a doctor’s advice.
BREAST FEEDING
The name is not recommended during breastfeeding. However, your doctor may prescribe it for you during breastfeeding if he/she feels that the benefit to you outweighs the risk. You should not take Diapride M 0.5 Tablet 15’s without a doctor’s advice.
DRIVING
Diapride M 0.5 Tablet 15’s may cause hypoglycaemia (low blood sugar levels) whose symptoms include unusual sleepiness, shivering, palpitations, sweating etc. This may affect your ability to drive. Use caution while driving or doing anything that requires concentration.
LIVER
If u have or had a history or evidence of any liver-related diseases, please consult the doctor before taking the medicine. The dose may have to be adjusted by your doctor.
KIDNEY
If u have or had a history or evidence of any kidney-related diseases, please consult the doctor before taking the medicine. The dose may have to be adjusted by your doctor.
Habit Forming
No
Diet & Lifestyle Advise
Fill your half plate with starchy veggies, a quarter with proteins, and a quarter with whole grain.
Eat at regular intervals. Do not take a long gap between a meal or snack.
Monitor your blood sugar level regularly especially when there are lots of fluctuations.
Invest at least 150 min of moderate-intensity physical activity or one hour and 15 minutes of high-intensity exercise every week.
Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
Replace refined carbohydrates containing foods with whole grain foods and increase the intake of fruits and veggies and other fiber-enriched foods.
Reduce intake of saturated fat (or hidden fats) in food like chips, crisps, pastries, biscuits, and samosas. Choose omega 3 fatty acid-containing oils for daily cooking. For frying, you can use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil.
Do not take stress as it may elevate your blood sugar level. You can adopt stress management techniques like mindfulness to control stress-related blood sugar changes.
Opt for low-fat dairy products (low-fat yogurt, fat-free milk, and cheese, etc.).
Keep your blood pressure as normal (140/90) as possible. As it reduces the risk of cardiovascular diseases in diabetes patients.
Special Advise
Keep taking the drug even if you think your blood sugar levels are under control. If you miss a dose, do not take a larger dose, consult your treating physician for advice.
Take short frequent meals, avoid prolonged fasting when taking this drug. Beware of symptoms of hypoglycaemia which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination etc. Whenever you experience the above-mentioned symptoms, immediately consume 5-6 candies or 3 glucose biscuits or 3 teaspoons of honey/sugar and also get in touch with your physician. Make sure to carry these with you at all times, especially for long travels.
It is always better that your physician knows about any underlying conditions like kidney disease or liver disease, prior heart attack, alcohol intake, etc before the doctor prescribes you this medicine.
Avoid drinking alcohol while on this drug as it increases the risk of hypoglycaemia (decrease in blood sugar which might be fatal in some cases) and lactic acidosis (when the lactic acid increases in the body which impacts the functioning of various organs in the body).
Try to quit smoking and reduce intake of carbohydrate-rich food like potato, rice, mangoes, bread, sugar etc.
Remember, lifestyle modifications are the most important step in controlling blood sugar levels.
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