CISPLAT 50MG contains cisplatin which belongs to group of medicines called anti-cancer drugs
What CISPLAT 50MG is used for?
It is used treat tumour of:
Testis
Ovary
Bladder
Head and neck epithelium
Lung
Cervix
Warning & Precautions
Talk to Doctor
Talk to your Doctor, if you:
Are allergic to any of the other ingredients of this medicine
Have severe kidney disease
Have hearing difficulties
Have very low numbers of blood cells (myelosuppression)
Are dehydrated
Need to have a vaccine for (yellow fever)
Have any symptoms of nerve damage (peripheral neuropathy) like pins and needles, numbness or poor sense of touch
Have or had radiation therapy to your head
Pregnancy & Breast Feeding
Due to the possible risk of birth defects female patients should take contraceptive measures both during treatment with cisplatin and for at least six months after treatment has ended
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before using this medicine
Driving & Using Machines
Do not drive or use machines if you experience any side effect which may lessen your ability to do so
Interactions
Tell your doctor if you are taking,
Cephalosporins, aminoglycosides, amphotericin B (used to treat infections)
Ifosfamide, bleomycin, methotrexate, paclitaxel (used to treat cancer)
Oral anticoagulants (used to treat blood clots)
Antihistamines (used to treat allergies, cold)
Phenytoin (used for the treatment of convulsions)
Directions & For Use
This medicine should only be given by a doctor
Side Effects
Serious
Sudden itchy rash (hives), swelling of the hands, feet, ankles, face, lips, mouth or throat (which may cause difficulty in swallowing or breathing) and you may feel you are going to faint
Severe chest pains possibly radiating to the jaw or arm with sweating, breathlessness and nausea (heart attack)
Pain or swelling at the injection site during the injection (may be due to the injection not going into the vein properly, which can lead to serious damage to the tissues around the injection site)
Stroke, brain dysfunction (confusion, slurred speech, sometimes blindness, memory loss and paralysis)
Common
Decrease in bone marrow function (affects the production of blood cells), decrease in white blood cells (leukopenia)
Decrease in blood platelets, increases the risk of bruising and bleeding (thrombocytopenia)
Reduction of red blood cells which can cause weakness and your skin to look pale (anemia)
Reduced level of sodium in the blood
High temperature
Severe pain or swelling in either of your legs, chest pain or difficulty breathing (possibly indicating harmful blood clots in a vein)
Fast, irregular or slow heart beats
Sepsis (blood poisoning)
Uncommon
Damage to the ear (ototoxicity)
Reduced level of magnesium in the blood
Abnormal sperm production
Rare
Increased risk of acute leukemia
Seizures (fits)
Fainting, headache, confusion and loss of vision
Loss of certain types of brain function, including brain dysfunction characterized by spasms and reduced level of consciousness
Inflammation of mucous membranes of the mouth (stomatitis)
Peripheral neuropathy of the sensory nerves (tickling, itching or tingling without cause and sometimes with loss of taste, touch, sight, sudden shooting pains from the neck through the back and into the legs when bending forward
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