Advog M 0.3 Tablet 10’s belongs to the class of anti-diabetic drugs. It is used in the treatment of type 2 diabetes mellitus. Diabetes mellitus is a metabolic disease that causes high blood sugar levels. It occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance) or the pancreas (an organ behind the stomach) produces little or no insulin at all.
Advog M 0.3 Tablet 10’s is composed of two medicines, namely voglibose and metformin. Voglibose belongs to the class of alpha-glucosidase inhibitors. It is used in the treatment of diabetes mellitus and acts by delaying glucose absorption. Metformin belongs to the class of biguanides and is used to manage blood sugar levels, particularly in obese patients.
Voglibose acts by inhibiting the intestinal enzymes, which break complex sugars into simple sugars such as glucose. This process prevents the rise of blood glucose levels. Metformin exhibits non pancreatic effect to reduce serum glucose levels without increasing insulin secretion. It is also known as an insulin sensitizer as it increases the effects of insulin. Metformin is considered to be a unique anti-diabetic drug since it does not cause hypoglycemia (lowered blood sugar levels).
Advog M 0.3 Tablet 10’s is an orally administered drug. Take this drug with food at regular intervals as prescribed by your doctor to avoid stomach upset. Do not crush, chew or break the tablet. Your doctor will decide the dosage form, and this may change timely depending on your blood sugar levels. Do not stop taking Advog M 0.3 Tablet 10’s on your own, since it may cause a rise in your blood sugar levels leading to other health issues like kidney damage, blindness and loss of limbs. The common side effects of Advog M 0.3 Tablet 10’s include nausea, vomiting, changes in taste, diarrhea, dizziness, stomach pain, shortness of breath, skin rash, bloating, and flatulence (intestinal wind/gas). Although not everyone experiences these side effects, if they occur, seek medical attention.
Before starting Advog M 0.3 Tablet 10’s, let your doctor know if you have any medical history of anaemia (low hemoglobin levels), seizures (fits), heart, kidney, and liver diseases. Advog M 0.3 Tablet 10’s does not cause hypoglycemia (low blood sugar levels). However, when used with other diabetic drugs like insulin or sulfonylureas, it can lead to hypoglycemia. Also, speak to your doctor if you are on restricted food or fluid intake since Advog M 0.3 Tablet 10’s causes dehydration, low blood sugar, and kidney damage. Do not take Advog M 0.3 Tablet 10’s if you have gastrointestinal diseases like ulcerative colitis or Crohn’s disease. Do not take or stop Advog M 0.3 Tablet 10’s, if the doctor did not advise you to do so.
Uses of Advog M 0.3 Tablet 10’s
Type 2 Diabetes mellitus
Medicinal Benefits
Advog M 0.3 Tablet 10’s is fixed dose medication used to treat type 2 diabetes mellitus. Voglibose belongs to the class of alpha-glucosidase inhibitors. It delays glucose absorption by inhibiting the intestinal enzymes, which break complex sugars into simple sugars such as glucose. This process prevents the rise of blood glucose levels immediately after meals.
Metformin belongs to the class of biguanides. It shows the non-pancreatic effect to reduce serum glucose levels without increasing the insulin secretion. It is also known as an insulin sensitizer as it increases the effects of insulin. It is considered to be a unique anti-diabetic drug since it does not lower the blood sugar levels. Metformin does not cause weight gain in most cases.
Directions for Use
Advog M 0.3 Tablet 10’s is available as an oral tablet formulation. Your doctor prescribes the dosage based on your disease conditions and tolerance. Do not chew, crush or break the tablet and swallow it as a whole with a glass of water. Take Advog M 0.3 Tablet 10’s preferably with a meal, since it lowers the blood sugar levels and causes gastrointestinal side effects. Your doctor may start the course with a low dose and gradually maintain an effective dose to achieve the required blood glucose control.
Storage
Store in a cool and dry place away from sunlight
Side Effects of Advog M 0.3 Tablet 10’s
Most of the side effects of Advog M 0.3 Tablet 10’s do not require medical attention and gradually resolve over time. Advog M 0.3 Tablet 10’s can cause common side effects like nausea, vomiting, changes in taste, diarrhea, dizziness, stomach pain, shortness of breath, skin rash, bloating, and flatulence (intestinal wind/gas). Seek medical advice if these side effects persist longer.
Some less common side effects of Advog M 0.3 Tablet 10’s include pneumatosis intestinalis (gas-filled cysts on the bowel wall) when used along with other alpha-gastrointestinal drugs and lactic acidosis (a rare, but serious metabolic complication of excess lactic acid in the blood that is caused by metformin accumulation).
The risk of lactic acidosis is high in people with kidney, liver, and heart diseases. It is essential to speak to your doctor about your medical history before you take Advog M 0.3 Tablet 10’s. If any of these side effects occur and persist longer, call your doctor for emergency treatment.
In-Depth Precautions and Warning
Drug Warnings
Advog M 0.3 Tablet 10’s may increase the risk of cardiovascular diseases and hypoglycemic conditions in renal and liver disease patients. It can cause pneumatosis intestinalis (gas-filled cysts on the bowel wall) when used along with other alpha-gastrointestinal drugs. It is advised to monitor the gastrointestinal side effects thoroughly to rule out the possibility of pneumatosis intestinalis.
Advog M 0.3 Tablet 10’s has an increased risk of lactic acidosis (a rare, but serious metabolic complication of excess lactic acid in the blood that is caused by metformin accumulation). The risk of lactic acidosis is high in older people with kidney, liver, and heart diseases. Hence, brief your medical history and take advice from your doctor before starting Advog M 0.3 Tablet 10’s. Avoid consuming excessive alcohol as it can potentiate lactic acidosis.
Drug Interactions
Drug-Drug Interaction: Advog M 0.3 Tablet 10’s may interact with anti-depressants (selegiline, isocarboxazid, phenelzine), anti-inflammatory drugs (prednisolone, phenylbutazone), drugs that treat fluid retention (metolazone, hydrochlorothiazide, chlorothiazide), medicines used to treat high blood pressure (propranolol, metoprolol), anabolic, and corticosteroids. Please check the instruction leaflet that comes with the medication before you take Advog M 0.3 Tablet 10’s.
Drug-Food Interaction: Limit alcohol intake since it affects blood sugar levels. Avoid fatty foods and include healthy carbohydrates in your diet.
Drug-Disease Interaction: Tell your doctor before taking Advog M 0.3 Tablet 10’s if you have a medical history of allergic reactions to medicines, heart diseases, liver, and kidney problems. Advog M 0.3 Tablet 10’s may cause pneumatosis intestinalis (gas-filled cysts on the bowel wall) when used along with other alpha-gastrointestinal drugs.
Safety Advice
ALCOHOL
CONSULT YOUR DOCTOR
It is unsafe to consume alcohol since it may worsen the side effects.
PREGNANCY
Advog M 0.3 Tablet 10’s may cause a risk in pregnancy. Please consult your doctor before starting Advog M 0.3 Tablet 10’s.
BREAST FEEDING
There is no sufficient data on how Advog M 0.3 Tablet 10’s affects breastfeeding. It is safe to seek medical advice before you start Advog M 0.3 Tablet 10’s if you are lactating.
DRIVING
Your driving ability may be affected if your blood sugar levels are too high or too low. Do not drive or operate machinery if you also experience dizziness or drowsiness.
LIVER
Let your doctor know if you have any history of liver diseases or hepatic impairment when you are prescribed Advog M 0.3 Tablet 10’s.
KIDNEY
Let your doctor know if you have any history of kidney diseases when you are prescribed Advog M 0.3 Tablet 10’s.
Habit Forming
No
Diet & Lifestyle Advise
Take the medication as directed by the doctor and at regular intervals if you take Advog M 0.3 Tablet 10’s for more than once per day. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Advog M 0.3 Tablet 10’s.
Maintain a fiber-rich diet and include healthy carbohydrates from fruits, vegetables, and whole grains to maintain your blood glucose levels.
Eat at regular intervals
Keep a check on your weight and exercise regularly to keep your heart healthy.
Your doctor also guides you how to notice and manage the early symptoms of high/low blood sugar levels.
Gastrointestinal side effects can be managed with simple modifications in your lifestyle. These include cutting down on sugars and fatty foods, avoiding carbonated drinks and foods that cause gas.
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