Abvida-M 50 mg/500 mg Tablet 15’s is a combination drug of Vildagliptin (DPP-4 inhibitor), and Metformin (Biguanides) belongs to the class of anti-diabetic. Type 2 diabetes mellitus used to be known as ‘non-insulin-dependent diabetes mellitus (NIDDM)’ or ‘maturity-onset diabetes’. Type 2 diabetes develops if the body does not produce enough insulin, or where the insulin that your body makes does not work as well as it should. It can also develop if the body produces too much glucagon. Insulin is a substance which helps to lower the level of sugar in your blood, especially after meals. Abvida-M 50 mg/500 mg Tablet 15’s is another substance which triggers the production of sugar by the liver, causing the blood sugar to rise. The pancreas makes both of these substances.
Abvida-M 50 mg/500 mg Tablet 15’s helps to control the blood sugar level. It works by making the pancreas produce insulin and less glucagon (effect of vildagliptin) and also by helping the body to make better use of the insulin it produces (effect of metformin). You must continue to follow the diet and exercise recommended for you whilst you are on treatment with Abvida-M 50 mg/500 mg Tablet 15’s. Abvida-M 50 mg/500 mg Tablet 15’s is not a substitute for insulin. It is not used to treat type 1 diabetes (where your body does not produce insulin at all), or diabetic ketoacidosis.
Abvida-M 50 mg/500 mg Tablet 15’s should be taken with food to avoid an upset stomach. Abvida-M 50 mg/500 mg Tablet 15’s should be taken at the same time of the day each time for best results. For better advice, your doctor will decide, what dose should be taken and it can change timely depending upon your condition. The most common side effect of Abvida-M 50 mg/500 mg Tablet 15’s is hypoglycemia (low blood glucose levels) characterised by dizziness, sweating, palpitations, hunger pangs, dry mouth and skin etc. So, to avoid hypoglycemia, you should not miss meals and also should carry some form of sugar along with you. Other side effects include taste change, nausea, diarrhoea, stomach pain, headache, upper respiratory symptoms.
Abvida-M 50 mg/500 mg Tablet 15’s should not be stopped even if you feel better, without consulting your doctor as sugar level keeps changing. If you stop taking Abvida-M 50 mg/500 mg Tablet 15’s abruptly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy) and nerve damage (neuropathy). Abvida-M 50 mg/500 mg Tablet 15’s should not be taken if you have type 1 diabetes mellitus, severe kidney or liver disease. Please inform your doctor if you have any heart disease, is or planning to get pregnant or breastfeeding.
Uses of Abvida-M 50 mg/500 mg Tablet 15’s
Type 2 Diabetes Mellitus
Medicinal Benefits
Abvida-M 50 mg/500 mg Tablet 15’s helps your pancreas to produce more insulin, make effective utilization of insulin, and decreases excess of sugar that your liver makes. It helps in controlling the rise of blood sugar level in your body after a meal. Abvida-M 50 mg/500 mg Tablet 15’s plays a vital role in controlling blood sugar levels and prevents serious complications of diabetes like eyesight loss (retinopathy), kidney (nephropathy), nerve damage (neuropathy), diabetic foot ulcer and delayed wound healing.
Directions for Use
Abvida-M 50 mg/500 mg Tablet 15’s should not be used unless prescribed by a doctor. Always take Abvida-M 50 mg/500 mg Tablet 15’s exactly as your doctor told you. Your doctor will advise you how often you take your tablets on the basis of your medical condition. Swallow the tablet with a full glass of water.
Storage
Store in a cool and dry place away from sunlight
Side Effects of Abvida-M 50 mg/500 mg Tablet 15’s
Every medicine has some sort of side effects. In the beginning days of the treatment with Abvida-M 50 mg/500 mg Tablet 15’s, you may suffer from low blood sugar, nausea, headache, shaking or quivering, vomiting, diarrhoea, pain in and around the stomach (abdominal pain), loss of appetite, joint pain, tiredness, constipation, swollen hands, ankle or feet (oedema). But these would be temporary and may be relieved after some time. However, if you still have discomfort speak with the doctor. Lactic acidosis (excess level of lactic acid in the blood) is a rare side effect which is serious and can lead to a life-threatening condition.
In-Depth Precautions and Warning
Drug Warnings
Abvida-M 50 mg/500 mg Tablet 15’s should not be used in patients with type 1 diabetes or with diabetic ketoacidosis. Some diabetic patients, while taking Abvida-M 50 mg/500 mg Tablet 15’s, might develop a rare but serious condition called lactic acidosis. In this condition, there is too much lactic acid accumulated in the blood that can damage the working of your liver and kidney required for the elimination of excess lactic acid from the blood. Before you start taking Abvida-M 50 mg/500 mg Tablet 15’s, tell your doctor if you’ve ever had pancreatitis (inflammation of the pancreas), kidney disease, and low vitamin B12 level. Abvida-M 50 mg/500 mg Tablet 15’s, when used with insulin, may extremely lower the blood sugar level leading to hypoglycaemia condition, which can be fatal. In this case, your doctor may adjust the dose by lowering the dose of insulin or Abvida-M 50 mg/500 mg Tablet 15’s. Prolonged intake of Abvida-M 50 mg/500 mg Tablet 15’s may lower your thyroid-stimulating hormone (TSH); hence, an annual check-up of TSH is recommended. In rare cases, you may also develop a serious skin reaction known as bullous pemphigoid that requires immediate medical attention. Tell your doctor if you are going to have a diagnostic test with an injection of dye or X-ray contrast agent. The use of Abvida-M 50 mg/500 mg Tablet 15’s should be stopped for a short time before having an X-ray procedure.
Drug Interactions
Drug-Drug Interaction: Abvida-M 50 mg/500 mg Tablet 15’s interacts with pain killers (aspirin, ibuprofen, and celecoxib), high blood pressure-lowering pills (nifedipine, captopril, enalapril, lisinopril), thyroid hormones (thyroxine), antacid (cimetidine) or certain medicines affecting the nervous system.
Drug-Food Interaction: Intake of excessive alcoholic beverages may increase the chance of life-threatening condition known as Lactic Acidosis. So, avoid intake of alcoholic beverages with Abvida-M 50 mg/500 mg Tablet 15’s.
Drug-Disease Interaction: People affected with heart diseases (like congestive heart failure and myocardial infarction), vitamin B12 deficiency, and alcoholism should avoid intake of Abvida-M 50 mg/500 mg Tablet 15’s.
Safety Advice
ALCOHOL
CONSULT YOUR DOCTOR
It is best to avoid alcohol while taking medication.
PREGNANCY
Please consult your doctor for advice before using Abvida-M 50 mg/500 mg Tablet 15’s.
BREAST FEEDING
Please consult your doctor for advice before using Abvida-M 50 mg/500 mg Tablet 15’s.
DRIVING
Drive only if you are physically stable and mentally focussed, If you experience drowsiness after taking these medications you should not drive or operate any machinery or vehicles.
LIVER
If u have or had history or evidence of any liver-related diseases, please consult the doctor before taking the medicine.
KIDNEY
If u have or had history or evidence of any kidney-related diseases, please consult the doctor before taking the medicine.
Habit Forming
No
Diet & Lifestyle Advise
Fill your half plate with starchy veggies, a quarter with proteins, and a quarter with whole grain.
Eat at regular intervals. Do not take a long gap between a meal or snack.
Monitor your blood sugar level regularly especially when there are lots of fluctuations.
Invest at least 150 min of moderate-intensity physical activity or one hour and 15 minutes of high-intensity exercise every week.
Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
Replace refined carbohydrates containing foods with whole grain foods and increase the intake of fruits and veggies and other fibre-enriched foods.
Reduce intake of saturated fat (or hidden fats) in food like chips, crisps, pastries, biscuits, and samosas. Choose omega 3 fatty acid-containing oils for daily cooking. For frying, you can use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil.
Do not take stress as it may elevate your blood sugar level. You can adopt stress management techniques like mindfulness to control stress-related blood sugar changes.
Opt for low-fat dairy products (low-fat yoghurt, fat-free milk, and cheese, etc.).
Keep your blood pressure as normal (140/90) as possible. As it reduces the risk of cardiovascular diseases in diabetes patients.
Special Advise
Contact your doctor immediately if you have nausea, vomiting, kussmaul breathing (laboured and deep), and generalised weakness which are symptoms of Lactic acidosis, a very rare but serious metabolic complication.
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